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As an important transcription factor, Nrf2 can not only regulate SLC7A11 transcription, but also up-regulate the expression of GSS and GCLC, which are key rate-limiting enzymes for GSH synthesis (Sun et al., 2016a

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The resulting hydrogel, despite its non-thermoresponsive precursors, was injectable through 23-gauge needles and exhibited thermoresponsive properties sustaining mucosal elevations up to 90 min